Mouth & Nasal Uses

This study investigated the ability of chlorine dioxide to eliminate Enterococcus faecalis from dentinal tubules of bovine incisors. Thirty-seven extracted bovine incisor roots were sectioned into seventy-four 5 mm disks. Standardized lumens were filled with either sterile Brain Heart Infusion Broth …

"The difference in effectiveness between the chlorine dioxide gas of Oracare and stabilized/precursor forms of chlorine dioxide (sodium chlorite) was evident as none of the mouthrinses using the latter inactivated significantly greater levels of VSCs than the water control." "The MICs for Oracare were higher than those for chlorhexidine when compared directly against a panel of 11 microbial species. However, when normalized to parts per million of the active ingredients, the Oracare rivaled the activity of chlorhexidine and exceeded it in activity toward the periodontal pathogen Aggregatibacter actinomycetemcomitans. The Oracare rinse removed a statistically higher percentage of VSCs than chlorhexidine"

"Snoot™ (Sinox Pharma, Inc.) at the ‘Original’ strength. This formulation ... yields between 60 parts per million (ppm) and 75 ppm (~0.01% wt/vol) ClO2 over the course of 12 hours," "DioxiRinse™ (Frontier Pharmaceutical, Inc.) to be used at the ‘Standard Strength’ yielding a concentration of ~40 ppm (0.006% wt/vol) ClO2. If an HCP has direct exposure to a cough or sneeze of individual with presumed COVID-19, immediate cleansing using both products is suggested, even if the recommended maximum use of 4 times in a 12-hour period is exceeded. However, 6 administrations in a 24-hour period are strongly discouraged."

Dentistry Today July/August 2020 Page 18

The aim of this study was to evaluate the effect of chlorine dioxide and various other more common irrigation solutions on the microhardness and surface roughness of root canal dentin. Fifty human maxillary central incisors were sectioned longitudinally and treated for 1 minute with 5 ml of the foll …

Chlorine dioxide whitens teeth at a faster rate than hydrogen peroxide. Specimens treated with chlorine dioxide were significantly lighter than those treated with hydrogen peroxide at the end of the first 2 min application cycle, however, extended exposures did not enhance color.

As the presence of dentin powder had a negative effect on the efficacy of disinfectants, the importance of elimination of dentin scrapings and smear layer from the root canal system during endodontic treatments is highly recommended. ClO 2 can be effective for a final rinse.

{Chlorine dioxide treatment}

While thereis no evidence that inactivating the COVID-19 virus in the mouth will impact disease transmission, the studiesreinforce the antimicrobial strength of ClōSYS products.Clinical trials in progress at the University of California San Francisco are evaluating whether oral rinses can reduce the viral load in the mouth, which mayin turn reduce the transmission of the disease.

--Includes comparison charts

**Includes pathogen levels. In another referenced study, ClōSYS safely reduced the exposure to microbial aerosols by 60%.

****!!!!*** "hypothesis as to why ClO2 is safe even in higher concentrations when added to the dental unit waterlines in order to minimize the virus transmission through dental aerosols."

If the mist in a dentist's office -- sent flying into the air by spinning, vibrating tools -- contains a virus or some other pathogen, it is a health hazard. So researchers studied the viscoelastic properties of food-grade polymers and discovered that the forces of a vibrating tool or dentist's drill are no match for them. Not only did a small admixture of polymers completely eliminate aerosolization, but it did so with ease.

List of Publications describing CloSYS technology & products download For Dry Mouth: Xerostomia: A common condition on the rise download Xerostomia: Help Patient Cope download For Mouth Sores: Oral Care for Mouth Sores download Oral Sores & Cancer Treatment download Helping Cancer Patients w/ oral mucositis dow

****** Volatile sulfur compounds impede wound healing."One way chlorine dioxide can improve cytokine immune response is to kill those ****pathogens which initiate pro-inflammatory cytokines." "Chlorine dioxide neutralizes not only VSCs but also the polyamines." "Hydrogen sulfide, the other major volatile sulfur compound, is mentioned for its ability to accelerate cell death partly through the increase of apoptotic p 53 proteins, and the promotion of an increase in reactive oxygen species through the decrease of SOD. Osteoblasts are suppressed by HS and this may be another way bone loss is initiated along with collagen loss. Even though chlorine dioxide is a free radical itself, this study also suggests that chlorine dioxide would stop the decrease in SOD and thus **promote anti-oxidant glutathione** levels and therefore the health in the tissues it affects by removing the hydrogen sulfide that causes reduction in SOD. The free radical effect of chlorine dioxide is brief but the removal of HS is prolonged."

In vitro laboratory analyses tested Closys Ultra Sensitive Oral Rinse's effectiveness in reducing SARS-CoV-2. The product does not use alcohol, hydrogen peroxide, or povidone iodine.

Disclosure: We value transparency at Today’s RDH. This article is sponsored content from OraCare as part of our sponsored partner program. According to Web MD, “we all need saliva to moisten and cleanse our mouths and digest food. Saliva also prevents infection by controlling bacteria and fungi in the mouth. When we don’t produce enough saliva, our […]

"A stable mouth wash or dentifrice composition containing stabilized chlorine dioxide and phosphates is disclosed for reducing the motility of and killing microbial pathogens. The preferred concentration ranges are between about 0.005% - 0.5% chlorine dioxide, and between about 0.02% - 3.0% phosphate. The phosphate retards escape of chlorine dioxide in the pH range (6.0 to 7.4) typically found in a mouth"

Active Chlorine Dioxide Oral Rinse (Patented) With so many mouth rinses to choose from, a choice can be a difficult one at best. Allow us to explain to you the difference and the importance of true,...

With research linking gingival inflammation to many systemic conditions, it's now more critical than ever to provide patients the information to make informed decisions.